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| Suffredini,Ivana Barbosa; Paciencia,Mateus Luís Barradas; Varella,Antonio Drauzio; Younes,Riad Naim. |
| Infections caused by multiresistant bacteria are a widespread problem, especially in intensive care units. New antibiotics are necessary, and we need to search for alternatives, including natural products. Brazil is one of the hottest spots in the world in terms of biodiversity, but little is known about the chemical and pharmacological properties of most of the plants found in the Amazon rain forest and the Atlantic Forest. We screened 1,220 organic and aqueous extracts, obtained from Amazon and Atlantic rain forest plants, against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa and E. coli. Seventeen organic and aqueous extracts obtained from 16 plants showed activity against both Gram-positive bacteria. None of the extracts showed... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Plant extract; Antibacterial activity; Amazon rain forest; Atlantic forest. |
| Ano: 2006 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702006000600008 |
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| Castilho,Adriana Lígia de; Silva,Juliana Paola Correa da; Saraceni,Cintia Helena Coury; Díaz,Ingrit Elida Collantes; Paciencia,Mateus Luís Barradas; Varella,Antonio Drauzio; Suffredini,Ivana Barbosa. |
| Previous studies analyzing 2,200 plant extracts indicated anti-enterococcal activity in 25 extracts obtained from Brazilian forests' plants. In the present study, these extracts were subjected to microdilution broth assay (MDBA) and disk diffusion assay (DDA) using planktonic Enterococcus faecalis ATCC® 29212TM and were submitted to phytochemical analysis in TLC and HPLC. Three extracts obtained from Ipomoea alba (MIC < 40 µg/mL), Diclinanona calycina (MIC < 40 µg/mL) and Moronobea coccinea (40 < MIC < 80 µg/mL; MBC = 80 µg/mL) showed significant bactericidal activity in the MDBA and four extracts obtained from I. alba (14.04 ± 0.55 mm diameter) S. globulifera (14.43 ± 0.33 mm and 12.18 ± 0.28 mm diameter) and Connarus ruber var. ruber (13.13 ±... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Enterococcus faecalis; Endodontitis; Antibacterial activity; Amazon rain forest; Bioprospection. |
| Ano: 2014 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822014000300002 |
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